What dose of cannabis gummies for sleep?
Start with 2.5 mg to 5 mg THC. For CBD, studies use 25 mg to 175 mg. Wait 2 hours before taking more. Oral gummies take 30 to 120 minutes to work. Peak effects arrive at 2 to 4 hours. Effects last 4 to 8 hours.
THC dose ranges
- 2.5 mg: light dose. Good first trial.
- 5 mg: standard dose for many adults.
- 10 mg: common package unit in states with legal cannabis. May cause anxiety or fast heart rate.
- 20 mg and above: high dose. Not for sleep unless you have tolerance.
CBD dose ranges
Clinical trials for anxiety and sleep use 25 mg to 175 mg per day. Some epilepsy trials use 10 mg to 20 mg per kg of body weight. Over-the-counter CBD gummies often hold 10 mg to 50 mg per piece. Evidence for CBD alone as a sleep aid is mixed. A 2019 review found small studies with weak methods.
CBN and other additives
CBN has little human data for sleep. Many gummies combine THC, CBD, and CBN in 1:1:1 ratios. No controlled trial shows CBN improves sleep in people. Treat CBN as an unknown.
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Factors that change your dose
- Body weight: higher weight may need more, but data is weak.
- Tolerance: daily use raises dose needs.
- Food: a fatty meal delays onset and raises peak blood levels.
- Liver function: liver enzymes CYP2C9 and CYP3A4 break down THC. Liver disease or drugs that block these enzymes raise blood levels.
- Age: adults over 65 may need half the dose.
Label accuracy
A 2015 study in JAMA found 75% of edible products had THC content that differed from the label by more than 10%. A 2020 follow-up found similar problems. Do not trust the number on the package. Start with half of one gummy if the label is uncertain.
Risks and interactions
THC can cause anxiety, paranoia, dry mouth, red eyes, fast heart rate, and impaired memory. High doses can cause vomiting and psychosis in some people. THC interacts with warfarin, clobazam, and other drugs. CBD blocks CYP enzymes and raises blood levels of some drugs. Check with a pharmacist if you take prescription medicine.
What to do if you take too much
Stay calm. Drink water. Do not drive. Most oral THC effects fade in 4 to 8 hours. Call Poison Control at 1-800-222-1222 if you have chest pain, severe vomiting, or hallucinations.
Legal notes
THC gummies are legal in some US states for adults 21 and over. Federal law bans THC above 0.3% on a dry weight basis. Hemp-derived CBD gummies with less than 0.3% THC are legal under federal law but not all states allow them.